The University Library is located in the McDonald buildiing near the corner of Harold and Dana Avenue. This building contains most the the library's collections, including archives and special collections. Services such as acquisitions, electronic reserves, interlibrary loan, and collection development are administered in the McDonald building. Circulation, reference and traditional reserves services are administered at the Connection Center in the Conaton Learning Commmons building. The Conaton building is located at the corner of Dana Avenue and Francis Xavier Way. The two buildings are joined together on the third and second floors of the McDonald building.

The juvenile and folio collections are located on the first floor of the McDonald building. The second floor contains periodicals with current issues and bound volumes together in one alphabetical display. Part of the main collection (PQ-Z) and audiovisuals are also housed on the second floor. The third floor contains the majority of the main collection (A-PQ) as well as reference, archives, and special collections. The McDonald Building provides study, lounge, conference, and instruction space with an emphasis on individual and quiet study. It houses photocopiers, computer workstations, and printers.

The Conaton Learning Commons also provides study, lounge, conference and instruction space with an emphasis on group study and collaboration. Also incuded in the Conaton Learning Commons is the Math Lab, Writing Center, Student Advising, Technical Help, and the Multimeda Lab.

For current members of the Xavier Community the library provides on-site and off-campus access to the XPLORE Library Catalog, more than 300 research databases, about 55,000 electronic journals, more than 67,000 electronic books, electronic reserves and the World Wide Web.